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Advanced Surfaces for Stem Cell Research

Edited by Ashutosh Tiwari, Bora Garipcan and Lokman Uzun
Series: Advanced Materials Series
Copyright: 2017   |   Status: Published
ISBN: 9781119242505  |  Hardcover  |  
480 pages | 49 illustrations
Price: $225 USD
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One Line Description
This book brings together innovative methodologies and strategies adopted in the research and development of advanced surfaces in stem cells.

Materials scientists, biologists, chemists, biomedical engineers in stem cell research, regenerative medicine and tissue engineering; industrial sectors working in advanced biosurface technology employing state-of-the-art stem cell techniques; and PhD and master level courses on surface materials processing, properties and applications.

Stem cells have attracted much attention in the fields of regenerative medicine and tissue engineering for their important role in the treatment of diseases. This is due to their unique properties such as their self-renewal capability and ability to differentiate into specific cell types. New research and therapies in these fields are mainly focused on a better understanding of the natural mechanisms of stem cells and the control and regulation of their behavior under in-vivo or in-vitro conditions.
Advanced Surfaces in Stem Cell Research first outlines the importance of Extra Cellular Matrix (ECM) which is a natural surface for most of cells. Subsequent chapters discuss the following subjects:
• The superficial mechanical and physical properties of matrix microenvironment as stem cell fate regulator
• Effects of mechanotransduction on stem cell behavior
• Modulation of stem cells behavior through bioactive surfaces
• Influence of controlled micro and nanoengineered surfaces on stem cell fate
• Nanostructured polymeric surfaces for stem cells
• Laser surface modification techniques and stem cells applications
• Plasma polymer deposition: A versatile tool for stem cell research
• Application of bioreactor concept and modeling techniques in bone regeneration and augmentation treatments
• Substrates and surfaces for control of pluripotent stem cell fate and function
• Application of biopolymer-based, surface modified devices in transplant medicine and tissue engineering
• Silk as a natural biopolymer for tissue engineering

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Author / Editor Details
Ashutosh Tiwari is Secretary General, International Association of Advanced Materials; Chairman and Managing Director of Tekidag AB (Innotech); Associate Professor and Group Leader, Smart Materials and Biodevices at the world premier Biosensors and Bioelectronics Centre, IFM-Linköping University; Editor-in-Chief, Advanced Materials Letters; a materials chemist and docent in the Applied Physics with the specialization of Biosensors and Bioelectronics from Linköping University, Sweden.

Bora Garipcan received his PhD in 2008 from Hacettepe University, Institute of Graduate and Applied Sciences Bioengineering Division, Ankara Turkey. His main research areas are in biomaterials, biomimetic materials and biosensors. He is member of the Boaziçi University, Institute of Biomedical Engineering since July 2011. He has 36 publications in international peer-reviewed journals and 4 invited book chapters.

Lokman Uzun is an Associate Professor at the Department of Chemistry, Biochemistry Division, Hacettepe University, Ankara, Turkey where he also received his PhD in 2008. He is the author of more than 75 articles in peer-review journals and is the Assistant Editor of Hacettepe’s Journal of Biology and Chemistry. He recently took up a fellowship with the Biosensors and Bioelectronics Centre, Linköping University, Sweden. His research interest is mainly in materials science, surface modification, affinity interaction, polymer science, especially molecularly imprinted polymers and their applications in biosensors, bioseparation, food safety, and the environmental sciences.

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Table of Contents
1 Extracellular Matrix Proteins for Stem Cell Fate
Betül Çelebi-Saltik
2 The Superficial Mechanical and Physical Properties of Matrix Microenvironment as Stem Cell Fate Regulator
Mohsen Shahrousvand, Gity Mir Mohamad Sadeghi and Ali Salimi
3 Effects of Mechanotransduction on Stem Cell Behavior
Bahar Bilgen and Sedat Odabas
4 Modulation of Stem Cells Behavior Through Bioactive Surfaces
Eduardo D. Gomes, Rita C. Assunção-Silva, Nuno Sousa, Nuno A. Silva and António J. Salgado
5 Influence of Controlled Micro- and Nanoengineered Environments on Stem Cell Fate
Anna Lagunas, David Caballero and Josep Samitier
6 Recent Advances in Nanostructured Polymeric Surface: Challenges and Frontiers in Stem Cells
Ilaria Armentano, Samantha Mattioli, Francesco Morena, Chiara Argentati, Sabata Martino, Luigi Torre and Josè Maria Kenny
7 Laser Surface Modification Techniques and Stem Cells Applications
Çağrı Kaan Akkan
8 Plasma Polymer Deposition: A Versatile Tool for Stem Cell Research
M. N. Macgregor-Ramiasa and K. Vasilev
9 Three-dimensional Printing Approaches for the Treatment of Critical-sized Bone Defects
Sara Salehi, Bilal A. Naved and Warren L. Grayson
10 Application of Bioreactor Concept and Modeling Techniques to Bone Regeneration and Augmentation Treatments
Oscar A. Deccó and Jésica I. Zuchuat
11 Stem Cell-based Medicinal Products: Regulatory Perspectives
Deniz Ozdil and Halil Murat Aydin
12 Substrates and Surfaces for Control of Pluripotent Stem Cell Fate and Function
Akshaya Srinivasan, Yi-Chin Toh, Xian Jun Loh and Wei Seong Toh
13 Silk as a Natural Biopolymer for Tissue Engineering
Ayşe Ak Can and Gamze Bölükbaşi Ateş
14 Applications of Biopolymer-based, Surface-modified Devices in Transplant Medicine and Tissue Engineering
Ashim Malhotra, Gulnaz Javan and Shivani Soni
15 Stem Cell Behavior on Microenvironment Mimicked Surfaces
M. Özgen Öztürk Öncel and Bora Garipcan

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Author/Editor Details
Table of Contents
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