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The Greening of Pharmaceutical Engineering Volume 1

Practice, Analysis, and Methodology
M.R. Islam, Jaan S. Islam, Gary M. Zatzman, M. Safiur Rahman, and M.A.H. Mughal
Series: The Greening of Pharmaceutical Engineering
Copyright: 2016   |   Status: Published
ISBN: 9780470626030  |  Hardcover  |  
784 pages
Price: $225 USD
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One Line Description
This state-of-the-art text covers some of the most hot-button issues in the pharmaceutical industry, covering new, greener processes for engineers, scientists, and students to move the pharmaceutical industry into sustainability.

Pharmacists, engineers, scientists, and researchers in the pharmaceutical industry, students and faculty in chemical engineering and medical departments.

From Professor Rafiq Islam and his team comes another penetrating and challenging work, a four-volume series exposing the wrong and dangerous pathways taken, including the sources of those pathways, to engineer another branch of contemporary science and technology to socially beneficial ends. Dr. Islam and his co-authors achieved notoriety for delving into the idea of sustainability in the petroleum industry, an industry long thought to be antithetical to such a concept. They developed a workable philosophy and created a new methodology and paradigm as a lens through which to see petroleum engineering.

In the current series of volumes on pharmaceutical engineering, Islam et al. come together one more time to apply the same principles of sustainability as a practical metric for similarly transforming pharmaceutical research and development. This series locates the root of the problem in the widely-accepted yet largely uninvestigated assumption that the natural order linking all living organisms is just another mechanical system albeit more complex than most such systems. In the same way that their work on energy resource management did, this study of the pharmaceutical industry illuminates the negative consequences flowing from an overly rigid focus on the purely mechanical aspects, especially regarding the negative consequences flowing from money-driven, tangibles-focused development when it comes to preventing disease and promoting sustainable healing of the body by whatever is already available in the body.

This ground-breaking series is a unique and state-of-the-art study that only appears here, within these pages. A fascinating study for the engineer, scientist, and pharmacist working in the pharmaceutical industry and interested in sustainability, it is also a valuable textbook for students and faculty studying these subjects.

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Author / Editor Details
M. R. Islam, PhD is a world-wide consultant on environment and energy-related issues. Dr. Islam is known as the most published engineer in the world. He is credited to have coined terms, such as “green petroleum” and “sustainable petroleum development” at a time when “sustainable petroleum” was considered to be an oxymoron. Dr. Islam’s most notable contributions are in the areas of sustainability, environmental integrity, and knowledge modeling, on which topic he has written dozens of books and over 700 research papers.

Jaan S. Islam has been active in research on the topics of science and social science. He is a co-author of the theory of mass, energy, time, and human thought material that formed the core of a number of books, including the current series. His previous works include Reconstituting the Curriculum (with M.R. Islam & Gary Zatzman)

Gary M. Zatzman has decades of investigative journalism and research experience, dozens of articles in technical journals, and four previously published books: Sustainable Resource Development, Sustainable Energy Pricing, Economics of Intangibles (with M.R. Islam), and Reconstituting the Curriculum (with M.R. & J.S. Islam).

M. Safiur Rahman, PhD is the principal scientific officer at Bangladesh Atomic Energy Commission in the field of environmental engineering. Since 2000, Dr. Rahman has been carrying out research works related to the distribution of toxic trace elements in surface and ground water, food chains and the environment for many government agencies and has published over 100 scientific articles and several books.

M.A.H. Mughal is a prominent philanthropist, author, speaker, mentor and a business consultant with 22 years of global experience with some of the world’s top companies. He is the author of many articles and is a Chartered Fellow of the British Computer Society and holds many professional designations.

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Table of Contents
Preface xvii
1 Introduction 1
1.1 Opening Remarks 1
1.2 Are We Trained to Develop Contempt for
Conscience and Addiction to Selfishness? 4
1.3 Metadata 5
Giving Up Honey and Promoting Aspartame
as the Cure, i.e., Dumping the Natural Option in
Favour of the Artificial One? 8
1.4.1 Physics as Mastermind of Aphenomenality 11
1.4.2 False promises 13
Premises of New Science Sufficient For Uncovering
or Establishing The Cause of Anything? 25
We Have Been Lied To? 28
A Starting-Point for Society-Wide Corruption 29
of the Foundations of Aphenomenal Science in the
Works of Newton (Part A) and Einstein (Part B) 30
the Discussion-So-Far 48
References and Bibliography, or: Now Previous
Knowledge Can Help 50
Appendix 1.1 51
PART ONE • The Political Economy of U.S.
Government-led Struggles to Control or Suppress
Alcohol, Tobacco and Drug Addiction 51
Appendix 1.1 60
PART TWO • Delinearizing the Anti-Colonial
Origins of the Corporatized American State and
Its Consequences for Contemporary Science
and Technology 60
2 Current State of the World of Big Pharma 65
2.1 Summary 65
2.2 Introduction 66
2.3 How We Got Here: A Delinearized History
of the Information Age 70
2.3.1 Agriculture and Development 74
2.3.2 Desertification 74
2.3.3 Ecosystem change 75
2.3.4 Fisheries 75
2.3.5 Deforestation 76
2.3.6 Marine Litter 77
2.3.7 Water Resources 78
2.3.8 Climate Change 83
2.4 Sociological Degeneration 90
2.5 The Deadliest 10 Diseases 94
2.5.1 Corporatization and Healthcare 94
2.5.2 Death, Health, and Lifestyle 100
2.6 Paradox and New Science 114
2.6.1 Obesity Paradox 115
2.6.2 Obesity/Mortality Paradox 115
2.6.3 Simpson's Paradox 116
2.6.4 Low Birth Weight Paradox 118
2.6.5 Prevention Paradox 119
2.6.6 The Novelty Paradox 121
2.6.7 The Paradox of Worsening Conditions
with Medications 121
2.6.8 The Prostate Paradox 122
2.6.9 The Health-Lifespan Paradox 122
2.6.10 Smoker’s Paradox 125
2.6.11 Paradox of the Natural 125
2.6.12 The French Paradox 126
2.6.13 Paradox of Aging 126
2.6.14 Paradox of Translational Medicine 127
2.6.15 Peto's Paradox 127
2.6.16 TGF-β Paradox 128
2.6.17 Hispanic Paradox 128
2.7 The Cost Of Drugs 128
2.8 “Non-Prescription” Drugs 131
2.8.1 Illicit Drug Use 137
2.8.2 Medical Costs 140
3 HSS®A® Degradation in New Science 143
3.1 Summary 143
3.2 Introduction 144
3.3 The HSS®A® (Honey → Sugar → Saccharin® → Aspartame®)
Pathway 147
3.3.1 Delinearized History of Honey 147
3.4 The Sugar Culture and Beyond 172
3.5 The Culture of the Artificial Sweetener 177
3.5.1 Delinearized History of Saccharin® and
the Money Trail 183
3.6 The Culture of Aspartame 194
3.6.1 Delinearized history of Aspartame 197
3.6.2 Timeline 199
3.6.3 The Hidden Epidemic of Aspartame 221
3.7 The Honey-Sugar-Saccharin-Aspartame Degradation
in Everything 227
3.7.1 Eurocentric Prejudice 232
3.7.2 Two Different Tracks of Cognition 240
3.7.3 The Scientific Cognition Model Used in Islam 250
3.7.4 Islamic Scholars Who Were Founders of
Their Fields 254
3.7.5 Purpose/Meaning of Life 262
3.7.6 What is True? 268
3.7.7 Origin of Universe 271
3.7.8 Dogma to Pragmatism 286
3.7.9 Deitification of Self 288
4 The Hopelessness of New Science 291
4.1 Summary 291
4.2 Introduction 292
4.3 Colony Collapse Disorder (CDC) 294
4.3.1 Facts About Honey and CCD 295
viii Contents
4.3.2 CCD in Relation to Science of Tangibles 305
4.3.3 Possible Causes of CCD 314
4.4 Incurable Disease 325
4.4.1 The Common Cold 326
4.4.2 Cancer 330
4.4.3 Asthma 370
4.4.4 HIV/AIDS 372
4.4.5 Diabetes 380
4.5 Diseases with Implications for Fundamental
Theoretical Concerns (Mass, Energy and HTM) 384
4.5.1 Violence and Mental Illness 390
4.5.2 Role of Vaccine and Lifestyle 392
4.6 The Need for the Science of Intangibles 397
4.7 The Need for Studying the Time Dimension in
Implicit Form 404
4.8 Assessing the Overall Performance of a Process 411
4.9 Aphenomenal Theories of Modern Era 422
4.10 The Law of Conservation of Mass and Energy 425
4.11 Toward Uncovering Knowledge 432
4.12 Conclusions 435
5 Mass, Energy and Time: A Delinearized History 437
5.1 Summary 437
5.2 Introduction 438
5.3 The Energy Crisis 440
5.3.1 Are Natural Resources Finite and
Human Needs Infinite? 442
5.3.2 The Peak Oil Theory and its Connections
to Population and Lifestyle 444
5.3.3 Evidence in Favor of the Peak Oil Theory 457
5.3.4 Historical Background: Foundations
of Peak Oil Theory 461
5.3.5 Petroleum in the Big Picture 473
5.3.6 Unconventional Oil and Gas Resources 480
5.4 Gas Hydrates 485
5.4.1 Deconstruction of Peak Oil Theory 489
5.5 Science of Healthy Energy and Mass 507
5.5.1 Role of water, air, clay and fire in
scientific characterization 507
5.5.2 Departure from Logical Thinking and The
Onset of Dogma in New Science 534
5.5.3 Standardization of an aphenomenon 541
Appendix 548
6 Newton & Einstein: A Delinearized Deconstruction 583
6.1 Summary 583
6.2 Introduction 583
6.3 Historical Context 587
6.3.1 Shedding Off Built-in Bias and
Anti-Knowledge Motive 589
6.3.2 A Reflection on the Purposes of Science 601
6.4 Time Conceptions, Tangible-Intangible Nexus, and
Social Roles of Knowledge 602
6.4.1 More About Time: Newton’s “Laws of Motion” –
Versus Nature’s 605
6.4.2 Science and the Problem of Linearized Time 610
6.4.3 Reproducibility and the Extinction of Time 612
6.4.4 The Long Term as an Infinite Summation of
“Short Terms”
6.4.5 Erasing History in Order to “Disappear” the
Long-Term and Enshrine the Steady State 617
6.4.6 First Interim “Time”-ly Conclusion: The
Anti-Nature Essence of Linearized Time 619
6.4.7 Second Interim “Time”-ly Conclusion:
Making Time Stand Still by Way of
Linearized Visualization of Space 620
6.5 What is New Versus what is Permitted: Science
and the Establishment? 622
6.5.1 “Laws” of Motion, Natural “Law” & Questions
of Mutability 622
6.5.2 Scientific Disinformation 629
6.5.3 Galileo’s Experimental Program: An Early
Example of the Nature-Science Approach 632
6.5.4 Implications of Einstein’s Theory of Relativity
on Newtonian Mechanics 637
6.6 Deconstruction of Einstein’s concept of reality,
mass, time, and energy 640
6.6.1 Origin of Aphenomenality 640
6.6.2 Reality of Einstein 649
6.7 Conclusions 654
7 The Nature-Science Approach: Conclusions of Book I 657
7.1 Summary 657
7.2 Introduction 659
7.2.1 The ‘Origin-Pathway’ Approach of
Nature-Science Versus The ‘Input-Output’
Approach of Engineering 659
7.2.2 Reference Frame and Dimensionality 660
7.2.3 Can “Lumped Parameters”Address Phenomena
of Only Partial Tangibility? 662
7.2.4 Standardizing Criteria and The Intangible
Aspects of Tangible Phenomena 662
7.2.5 Some Retrograde Consequences of Eurocentric
Bias for New Science 664
7.3 Struggle for Social Reform: Internal and External Factors 666
7.4 Consequences of Nature-Science for Classical
Set Theory and Conventional Notions of Mensuration 668
7.5 Conclusions 670
7.5.1 Summary 670
7.5.2 Conclusions (in detail) 674
7.5.3 Tangible/Intangible Conundrum or
Yin Yang Cycle 675
7.5.4 Honey-Sugar-Saccharine-Aspartame (HSSA)
Degradation 677
7.5.5 Origin of Addiction 677
7.5.6 Origin of Ailments 678
7.5.7 The Role of Medical Intervention 681
7.5.8 Hopelessness of Modern Medical Science
and Medical Diagnosis 683
7.5.9 Cause of Disease and Irreversible Environmental
Damage 689
7.5.10 Greening of Pharmaceutical Industry 691
7.6 The Need for Change 701
7.7 The Nature Science Approach 702
References and Bibliography 705
Index 000

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MED071000: MEDICAL / Pharmacology
TEC009010: TECHNOLOGY & ENGINEERING / Chemical & Biochemical
SCI013060: SCIENCE / Chemistry / Industrial & Technical
TDCW: Pharmaceutical technology
MMG: Pharmacology
RNU: Sustainability

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